Mandrax Quaalude are a synthetic, barbiturate-like, central nervous system depressant. Methaqualone is an anxiolytic and a sedative-hypnotic drug. Quaaludes were introduced as a safe barbiturate substitute, but they later showed that the possibility of addiction and withdrawal symptoms were similar to those of barbiturates.
Methaqualone is a soothing that expands the action of the GABA receptors in the mind and sensory system. At the point when GABA action is expanded, circulatory strain drops and the breathing and heartbeat rates moderate, prompting a condition of profound unwinding. These properties clarify why methaqualone was initially for the most part endorsed for sleep deprivation. Methaqualone crests in the circulatory system inside a few hours, with a half-existence of 20–60 hours. Ordinary clients develop a physical resilience, requiring bigger portions for a similar impact. Overdose can prompt sensory system shutdown, trance state and demise. Methaqualone isn’t suggested for use while pregnant and is in pregnancy.
Uses of Mandrax Quaalude
In prescribed doses, Mandrax Quaalude promotes relaxation, sleepiness and sometimes a feeling of euphoria. It causes a drop in blood pressure and slows the pulse rate. These properties are the reason why it was initially thought to be a useful sedative and anxiolytic.
In 1972, Mandrax Quaalude were one of the most prescribed sedatives in United States.
It became a recreational drug due to its euphoric effect. Mandrax Quaalude were a popular drug of abuse during much of the 1970s, even though both the United States and Britain tightened control around their use and dispensing. “Luding out” where Quaaludes were taken with wine, became a popular college pastime.
When it was a legal medicine, methaqualone was available in tablet and capsule form and came in different strengths.
Mandrax Quaalude dosages was 75-150mg for light sedation. A common prescribed dose was 300mg. Up to 600mg was used for strong sedation. Tolerance develops rapidly and some users may take up to 2000mg daily to achieve the same effects.
Onset of action is approximately 30 minutes after taking Mandrax Quaalude and duration of action is between 5 to 8 hours.
Overdose of Mandrax Quaalude can lead to seizures, coma or death.
Taking doses of over 300 mg can be dangerous for first time users. Depending on the state of the user’s tolerance, doses of about 8,000 mg per day can be fatal and others on even higher doses (of up to 20,000mg) may survive.
Death can result at much lower doses if Mandrax Quaalude are taken with alcohol, which is also a central nervous system depressant.
Quaaludes use during Pregnancy and Breastfeeding
Quaaludes are not recommended during pregnancy as the effects on human fetal development are not clear.
There is no data available about the effects of Quaaludes in breastfeeding.
Quaaludes should not be taken with alcohol or with other central nervous system depressants. This increases the depressant effects and depending on the doses taken it can be fatal.
Do not drive or operate machinery while taking Quaaludes.